Human Embryology and Developmental Biology: With STUDENT CONSULT Online Access, 5e

Human Embryology and Developmental Biology: With STUDENT CONSULT Online Access, 5e

Language: English

Pages: 520

ISBN: 1455727946

Format: PDF / Kindle (mobi) / ePub

Master the concepts you need to know with Human Embryology and Developmental Biology. Dr. Bruce M. Carlson's clear explanations provide an easy-to-follow "road map" through the most up-to-date scientific knowledge, giving you a deeper understanding of the key information you need to know for your courses, exams, and ultimately clinical practice.

  • Visualize normal and abnormal development
  • with hundreds of superb clinical photos and embryological drawings.

  • Access the fully searchable text online, view animations, answer self-assessment questions, and much more at
  • Grasp the molecular basis of embryology
  • , including the processes of branching and folding - essential knowledge for determining the root of many abnormalities.

  • Understand the clinical manifestations of developmental abnormalities with clinical vignettes and Clinical Correlations boxes throughout.

Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

















afterbirth. The fetal surface of the placenta is smooth, shiny, and grayish because of the amnion that covers the fetal side of the chorionic plate. The maternal surface is a dull red and may be punctuated with blood clots. The maternal surface of the placenta must be examined carefully because if a cotyledon is missing and is retained in the uterine wall, it could cause serious postpartum bleeding. Recognition of certain types of placental diseases can provide valuable clues to intrauterine

chromatin, and early signs of breaking up of the nuclear membrane. In these cells, the bundles of keratin become more prominent, and the molecular weights of keratins that are synthesized are higher than in less mature keratinocytes. *Many types of tissues contain a population of stem cells, which have a high capacity for proliferation. Some of the daughter cells remain as stem cells, but other daughter cells become what in the epidermis are called transit-amplifying cells. These cells, which

appropriate epidermal appendages. Similarly, isolated subectodermal mesenchyme retains its embryonic character without differentiating into dermis. If ectoderm from one part of the body is combined with dermis from another area, the ectoderm differentiates into a regional pattern characteristic of underlying dermis, rather than a pattern appropriate for the site of origin of the ectoderm (Fig. 9.6). Cross-species recombination experiments have shown that, even in distantly related animals, skin

Four blastomeres. C, Twelve blastomeres. D, Morula in late stage of compaction (5 days). Note the indistinct cell outlines. (From Veeck LL, Zaninovic N: An atlas of human blastocysts, Boca Raton, Fla, 2003, Parthenon.) from these gametes. Epigenetic control is not confined to methylation patterns. Even as early as the zygote, different patterns of histone association with the chromatin account for pronounced differences in gene expression between the male and female pronuclei. For the first

7.10). Establishing the Uteroplacental Circulation Gross Relationships of Chorionic and Decidual Tissues One of the critical features of the developing embryonicmaternal interface is the establishment of a uteroplacental circulation that serves as the medium for bringing food and oxygen to and removing wastes from the embryo. This is accomplished by erosion of the walls of the spiral arteries of the uterus and their modification so that, as the embryo grows, these arteries can provide an

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